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Pyruvate Supplement Information

Pyruvate is a form of an organic acid called pyruvic acid. Pyruvate is involved in energy synthesis in most living organisms. It is not considered an essential nutrient since it can be produced in the cells of the body. Pyruvate, however, is consumed in the daily diet. Most individuals consume between 100 milligrams to 2 grams per day. Pyruvate can be found in high concentration in a few fruits (apples) and vegetables, as well as in dark beer and red wine.

It is believed that pyruvate may aid weight loss efforts. One study showed that 22-44 grams per day of pyruvate enhanced weight loss and resulted in a greater reduction of body fat in overweight adults when combined with a low-fat diet. Similar studies that employed 6-10 grams of pyruvate per day combined with an exercise program also lost weight. A few clinical studies suggest that pyruvate supplementation leads to weight loss by increasing the resting metabolic rate. However, pyruvate's effectiveness as weightloss supplement has not been substantiated.

Current research suugests that pyruvate might help some obese individuals lower their blood pressure and it may favorably modify lipid profiles. It also appears to enhance exercise endurance in some and may be protective in others with cardiac ischemia. It has been suggested that pyruvate might even have an ability to reduce insulin resistance.

Preliminary research suggests that pyruvate is an antioxidant, inhibiting the production of harmful free radicals.

Dosage and Administration

Those using pyruvate to loose weight have been known to take at least 30 grams per day. However, the most current research suggests a dose of 5 to 6 grams daily for a possible bariatric action or for athletic use.