Pycnogenol Information and Uses

Pycnogenol® is a liquid extract from the bark of the French maritime pine grown in Europe's largest single forest, spread over the coastal region of south-west France, les Landes de Gascogne. Although the term pycnogenol is now confined to procyanidins from the French maritime pine, the term was originally intended to serve as scientific name for this class of flavonoids.

Laboratory studies have demonstrated that pycnogenol has a number of antioxidant effects. Similar studies also indicate that pycnogenol has anti-inflammatory effects. All of pycnogenol's effects are thought to be due, in large part, to pycnogenol's capacity as a scavenger of reactive oxygen and reactive nitrogen species. Additionally, pycnogenol also appears to have the ability to inhibit the property functioning of NF-kappa B and AP-1. NF-kappa B and AP-1 upregulate the expression of several inflammatory agents such as intercellular adhesion molecule-1 (ICAM-1) .

Many claim that pycnogenol is useful for boosting the immune system, relieving neuro-degenerative disorders, is an anti-allergen, an anti-diabetic agent, relieves arthritis, prevents liver cirrhosis, and fights arthritis; however, these claims are not well founded. Recent research suggests that pycnogenol may indeed have some cardio protective effects useful for fighting a few vascular disorders.

Dosage and Administration

Common dosage ranges from 25 to 200 mg per day.