Pantethine Facts and Information

Pantethine is a highly absorbable and biologically active form of pantopthenic acid (vitamin B-5). Pantethine forms the reactive component of Coenzyme A (CoA) and the acyl-carrier protein (ACP). CoA and ACP are extensively involved in carbohydrate, lipid, and amino acid metabolism. It is also essential in producing, transporting, and releasing energy from fats and has been reported to lower blood levels of cholesterol and triglycerides.

Some studies indicate that pantethine may favorably affect lipids and protect against forms of cardio muscular disease. Additionally, it has been shown to protect against a number of toxins, including alcohol. Preliminary research leads researchers to believe that pantethine may influence various central nervous system and adrenal junctions, but no useful conclusions can yet be drawn from these early investigations. While it has been suggested in some published articles that pantethine supplementation may enhance exercise performance and inhibits hair loss and graying of hair, there is no evidence to suggest that either of these claims are true.


While most healthy people do not require additional amounts of pancreatin, the 10-25 mg found in some multivitamin supplements might improve levels of pantothenic acid (pancreatin). Possible lipid-lowering dosage typically ranges from 600 to 1,200 milligrams daily, taken in divided doses.