HMB Supplement Benefits and Side effects

Beta-hydroxy-beta-methylbutyrate, also known as HMB, is a substance naturally found in living organisms as a metabolite of the essential amino acid L-leucine. It has been reported, based on preliminary findings, that HMB may possess anticatabolic and immunomodulatory properties. HMB is a popular nutritional supplement among athletes involved in intense physical activity.

Suggested Benefits of HMB

Similar to other amino acids, HMB appears to play a role in the synthesis of certain proteins, including the type protein used by the body to build muscle tissue.

Animal studies suggest that HMB may be able to improve the growth of lean muscle tissue. However, these findings have not been substantiated by human studies and there is no conclusive evidence to support the link between HMB and increased muscle development and endurance in athletes. Notwithstanding, one study involving participants in a weight-lifting program who were given 3 grams of supplemental HMB, when compared to a placebo group, experienced greater gains in muscle mass and strength. However, a double-blind controlled trial found no effect of 3 grams per day of HMB for four weeks on body composition or exercise performance in 41 weight-training football players.

Dosage and Administration

Most people do not need to use HMB. For those involved in regular exercise that do choose to take this supplement, the research generally uses 3 grams of HMB per day in combination with resistive exercise, such as weight lifting.