Chondroitin Sulfate Information Guide

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Chondroitin sulfate is made of molecules called glycosaminoglycans, also known as GAGs. Chondroitin sulfate is essential in providing structure, water, and nutrients to cartilage. Most importantly, chondroitin sulfate allows molecules to move through cartilage, a very important property, as cartilage does not receive direct blood supply.

Studies indicate that chondroitin sulfate may promote healing of bone. In numerous studies, chondroitin sulfate has shown to relieve many symptoms and to even slow or reverse osteoarthritis. Additionally, chondroitin sulfate may lower blood cholesterol levels and help to prevent heart attacks in people who already have atherosclerosis.

Chondroitin sulfate is rich in sulfur and is related to glucosamine. GAGs affect how the body processes oxalate, a substance linked to kidney stones. In a study of 40 people with a history of kidney stones, it appeared that 30 mg doses twice a day of mixed GAGs reduced urinary oxalate excretion in 15 days, a change that could drop the risk of stone formation. However, studies on the effect of GAGs on kidney stone formation are not conclusive or substantiated.

Chondroitin Sulfate Supplementation

For atherosclerosis, 5 grams of chondroitin sulfate twice per day with meals and then lowering the amount to 500 mg three times per day after a few months, is not unheard of. Before taking such high amounts however, people should consult a doctor. For osteoarthritis, a normal level is 400 mg three times per day.

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